SERMs (Selective Estrogen Receptor Modulators) are a group of medications that impact the estrogen levels in the body. For decades, these medications have been around and used to deal with certain estrogen-related health conditions. Enclomiphene buy is a popular SERM that helps treat the condition of hypogonadism and aids in regulating blood testosterone levels.

In this blog, we’ll walk you through how SERMs work in the body and how effective they are in treating certain diseases. Let us get you straight into the details!

SERMs – What are They?

SERMs are man-made hormonal medications that are commonly prescribed to patients who have osteoporosis after menopause, its symptoms, and breast cancer. The most common SERM medications are:

• Raloxifene (Evista): This SERM medication is usually prescribed to Osteoporosis patients. Plus this drug is also effective in preventing the risk of breast cancer.
• Tamoxifen (Soltamox): Often, this drug is effective in treating ER-positive breast cancer – a type of breast cancer that grows with elevated levels of estrogen.
• Ospemifene (Osphena): Osphena is a SERM used to treat vaginal dryness that leads to pain reduction in intercourse. This happens usually in women suffering from menopause or close to it.
• Toremifene (Fareston): Toremifene is beneficial in the treatment of metastatic estrogen-receptor-positive breast cancer.
• Clomiphene: This medication helps women who haven’t gone through menopause but are suffering from infertility. It helps in inducing ovulation in females.
• Enclomiphene: This medication helps in treating the low testosterone levels in males and helps in regulating testosterone levels.

How Does SERMs Work?

In simple words, SERMs work by activating or blocking the body’s estrogen. These estrogen receptors react differently to the estrogen in several parts of the body.

Notably, some SERMs impact the bones and breast, while others have more impact on the uterus. This indicates that the SERMs are selective in their action and work in the body where it is needed. This makes SERMs helpful in a variety of health conditions. Have a look at a few examples:

Fertility

Clomiphene is a SERM that blocks the production of estrogen in the body. It activates the pituitary gland for the production of more follicle-stimulating hormones and other useful hormones in the ovaries. This entire process is helpful in the regulation of women’s monthly cycle and regulates ovulation. This also aids in the release of eggs at the right time.

Osteoporosis

SERMs are able to activate estrogen receptors in the bones. Usually, this helps in strengthening the bones. However, once the menopause stage is achieved, body estrogen levels might drop, thereby losing bone density and leading to osteoporosis.

SERMs mimic the activity of estrogen in bones and activate the positive effects of estrogen in the body. This helps in improving bone density and decreases the risk of bone fractures.

Breast Cancer

SERMs possess the ability to bind with the estrogen receptors in breast cells. This prevents the body from producing its own estrogen

to them. Since SERMs attach to the estrogen receptor instead of the natural estrogen in the body, they prohibit the production of cancer cells and stop them from spreading and growing.

Final Wordings

SERMs are a unique and beneficial class of medication that have a variety of impacts on the human body. These impacts are helpful in treating several estrogen-related conditions in the body. However, it is always better to discuss your medical condition with your healthcare provider and take medication in the right dosage.